Having healthy brain tissue, diseased tissue from the original surgery and autopsy tissue gives researchers the complete picture of the metamorphosis of a child’s disease. For example, it was only recently discovered that in recurrent medulloblastoma the child dies from a tumor that is completely different than the original tumor he/she was diagnosed with. This discovery was only made possible because of autopsy tissue donations. This discovery has changed the standard of care for recurrent medulloblastoma patients.